HPMC hydroxypropyl methylcellulose has become one of the largest pharmaceutical excipients at home and abroad, because HPMC has advantages that other excipients do not have.

1. Water solubility

It is soluble in cold water below 40 ℃ or 70% ethanol, and it is basically insoluble in hot water above 60 ℃, but it can be gelled.

2. Chemically inert

HPMC is a kind of non-ionic cellulose ether. Its solution does not carry ionic charge and does not interact with metal salts or ionic organic compounds. Therefore, other excipients do not react with it during the preparation process.

3. Stability

It is relatively stable to acid and alkali, and can be stored for a long time between pH 3 ～11, and its viscosity has no obvious change. The aqueous solution of HPMC has anti-mildew effect and can maintain good viscosity stability during long-term storage. The pharmaceutical excipients using HPMC have better quality stability than those using traditional excipients (such as dextrin, starch, etc.).

4. Adjustability of viscosity

Different viscosity derivatives of HPMC can be mixed in different proportions, and its viscosity can change according to a certain rule, and has a good linear relationship, so it can be selected according to the demand. 2.5 Metabolic inertia HPMC is not absorbed or metabolized in the body, and does not provide calories, so it is a safe excipient for medicinal preparations. .

5. Security

It is generally considered that HPMC is non-toxic and non-irritating material.

Pharmaceutical-grade HPMC is an important raw material for the production of sustained and controlled release preparations. It is a pharmaceutical excipient supported by the state for research and development, and is in line with the development direction supported by the national industrial policy. Pharmaceutical-grade HPMC is the main raw material for the production of HPMC plant capsules, accounting for more than 90% of the raw materials of HPMC plant capsules. The manufactured plant capsules have the advantages of safety and hygiene, wide applicability, no risk of cross-linking reaction, and high stability, which are in line with consumer expectations. The safety and sanitation requirements of food and medicine are one of the important supplements and ideal substitute products for animal gelatin capsules.